Closed-tube processing
Processing takes place inside the tube. The tube closure and instrument cover help contain the sample during homogenisation.
Homogenisation inside the sample tube
ProbeAX Evolution
Disposable tubes for processing tissue, biopsy, cartilage and bone samples with SpinAX. A ceramic element and the metal rasp inside the cap perform the grinding action.
- Manufacturer
- Axon Biotech GmbH
- Compatible instrument
- SpinAX · AL0500
- Nominal volume
- 40 ml for the EVO family
In the daily workflow
Packaging options
Single-wrapped tubes without saline or with 5 ml 0.85% NaCl, plus double blister packaging.
Additional sterile family
Axonlab also lists ProbeAX Evolution sterile AL0513-B under separate instructions. Choose the configuration by its exact reference.
Technical profile
The details.
Clearly stated.
- Manufacturer
- Axon Biotech GmbH
- Compatible instrument
- SpinAX · AL0500
- Nominal volume
- 40 ml for the EVO family
- AL0510 / AL0511-B solution
- 5 ml NaCl 0.85%
- Pack
- 50 pieces
- Applications
- Preparation for subculture and molecular diagnostics
Ordering references
References & variants
AL0509Without NaCl; single wrapped; 50Axonlab · 12082024
AL05105 ml 0.85% NaCl; single wrapped; 50Axonlab · 12051306
AL0511-B5 ml 0.85% NaCl; double blister; 50Axonlab · 12085203
AL0511Double wrapped, listed in 2025 brochure; confirm current availabilityBrochure reference
AL0513-BSterile; double blister; 50Axonlab · 12108677
DOCUMENTATION
Brochures and documents
Studies, publications and congress presentations (14)
PDFComparison of human tissue processing methods for maximal bacterial recoveryEur J Clin Microbiol Infect Dis · 2019 · Askar et al.PDFAnalytical and clinical performance report: ProbeAX Evolution / SpinAXADMED Microbiologie, Switzerland · 12/2023PDFTissue and blood cultures in periprosthetic and implant infections · ENBachelor thesis · fhg Tirol · 2024 · English translationPDFTissue and blood cultures in periprosthetic and implant infections · DEBachelor thesis · fhg Tirol · 2024 · originalPDFPerformance of three ready-to-use bottles for grinding orthopaedic samples · ENOral presentation · CRIOAc 2025 · Hospices Civils de LyonPDFPerformance of three ready-to-use bottles for grinding orthopaedic samples · FROral presentation · CRIOAc 2025 · Hospices Civils de LyonPDFImproved method for biopsy homogenisation and rapid detection of infections · GreekPoster · EBJIS 2024 · Karolinska · Greek versionPDFImproved method for biopsy homogenisation and rapid detection of infections · ENPoster · EBJIS 2024 · KarolinskaPDFHomogenisation and deep tissue biopsy for adequate microbiological diagnosis of wounds · Greeke-Poster · EBJIS 2025 · L. Sacco Hospital, Milan · Greek versionPDFHomogenisation and deep tissue biopsy for adequate microbiological diagnosis of wounds · ENe-Poster · EBJIS 2025 · L. Sacco Hospital, MilanPDFAnalytical performance evaluation of a new homogenisation system for tissue biopsiesPoster · SSM 2024 · ADMED (Scherler, Croxatto)PDFFungal growth on agar with and without SpinAX sample preparationPoster P53 · Kantonsspital Aarau, SwitzerlandPDFEvaluation of three ready-to-use bottles for orthopaedic samples · FRPoster P-024 · RICAI 2025 · Hospices Civils de LyonPDFMicrobial yield from infected tissues pretreated by various methodsBMC Musculoskeletal Disorders · 2021 · Cai et al.
Brochures and instructions for use (4)
Standard and sterile versions
July 2024 instructions cover AL0509, AL0510, AL0511 and AL0511-B. October 2025 instructions cover sterile AL0512, AL0513 and AL0513-B. Packs contain 50 tubes. AL0509 is supplied without NaCl; AL0510, AL0511 and AL0511-B contain 5 ml 0.85% NaCl. Unopened tubes are stored at +4 to +25 °C and used exclusively with SpinAX AL0500.
Ask about this productFrom the sample. To the laboratory workflow.
EDUCATIONAL MATERIAL · AHEPA HOSPITAL
The AHEPA demonstration shows how the ProbeAX Evolution tube is loaded into SpinAX and how the homogenisation cycle is started. The system is used according to the current manufacturer’s instructions.
- Remove the magnetic cover and load the closed tube upside down into the holder.
- Replace the cover and check the setting for the specific sample type.
- Start the automatic cycle. Homogenisation takes place inside the same tube.
- Proceed to the next laboratory method under the validated protocol.
How long is the cycle?
The AHEPA demonstration uses a one-minute cycle. The ProbeAX Evolution instructions, version 03 (05/07/2024), for AL0509/AL0510/AL0511/AL0511-B recommend one minute for standard samples, a sample weight of 500 mg, and adjustment to sample type and size. The current Axonlab AL0510 page, checked on 23/10/2026, describes the classic configuration with 5 ml of 0.85% NaCl and a two-minute grinding time. Confirm the exact reference, current instructions and the laboratory’s validated protocol before use.
What about PCR and NGS?
The ProbeAX Evolution flyer lists subculture and molecular diagnostics. Its instructions require prompt downstream microbiological and molecular methods under internal laboratory procedures. Axonlab describes AL0510 as tested DNA-free for molecular analyses. Compatibility and optimisation of a specific method must be confirmed by the laboratory with the technical team.
How are transport and storage determined?
ProbeAX instructions require a securely tightened cap, tissue completely covered by liquid and transport to the laboratory as quickly as possible. Processing and subsequent microbiological or molecular analyses follow internal laboratory procedures.
The workflow in practice.
FROM THE DEMONSTRATIONS
Loading and cycle
The Greek demonstrations show the disposable ProbeAX Evolution tube loaded upside down in the SpinAX holder after removing the magnetic cover. The cover is replaced, the duration checked and the automatic cycle started. In these examples, a one-minute cycle is selected. Cycle duration depends on the specimen and consumable reference. Follow current instructions and the laboratory’s validated protocol.
Grinding mechanism
The presentations describe alternating clockwise and anticlockwise SpinAX motion. The ProbeAX Evolution tube contains a ceramic element and a metal grinding surface in the cap for mechanical homogenisation. The disposable tube and reusable instrument are separate products.
Sample retrieval
The Greek demonstration shows homogenised material retrieved with a pipette or syringe in an appropriate laboratory setting before downstream analysis. Follow current manufacturer instructions and the laboratory’s validated protocol for handling and storage.
Culture and molecular analysis
Axonlab presents ProbeAX Evolution and SpinAX for sample preparation before culture or molecular analysis. Suitability for a specific PCR or NGS test requires separate validation based on the sample, method and reagents.
Ask about the workflowOfficial film · Axonlab · 01:22
SpinAX + ProbeAX.
See the workflow.
SpinAX and ProbeAX Evolution tubes in action, in Axonlab’s complete product demonstration.
Original Axonlab film · Press play for picture and sound.
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